Eastern and southern Africa remains the region most affected by the HIV epidemic in the world and accounts for more than 50% of the global burden of HIV. Significant progress has been made in recent years in the response to the epidemic in the region: new HIV infections and AIDS deaths have fallen while prevention and treatment services for HIV have increased substantially. While several challenges still remain, there is renewed optimism that the elimination of HIV and AIDS is not an impossible goal.
One of the major obstacles to preventing HIV-transmission has been the lack of an effective, female controlled method of prevention. Now, for the first time, a vaginal microbicide has been shown to reduce the risk of infection in women. CAPRISA 004 was a randomized placebo-controlled trial to assess the effectiveness and safety of a 1% Read More
Effective planning and delivery of HIV prevention programs depends on an understanding of where new infections are occurring and on the behaviours associated with those infections. A simple mathematical model developed by the UNAIDS Reference Group for Estimates, Modelling and Projections helps countries estimate the proportion of new infections that occur through key transmission modes. This type of in-country analysis could be used to inform the planning of appropriately targeted intervention programmes. However, improved biological and behavioural surveillance in countries is needed to provide more reliable data for input into such analyses.