Published on March 17, 2015 by

Viral load versus CD4 monitoring of ART in HIV-positive children

As coverage of paediatric ART increases and guidelines for ART initiation change, it will be necessary to determine how best to monitor ART. Routine monitoring of HIV viral load is common practice in ART programmes in high-income countries, but, in sub-Saharan Africa, most ART programmes rely on CD4 cell measurements or clinical monitoring to detect treatment failure. We conducted a computer simulation of HIV-positive children to predict the effect of different ART monitoring strategies.