Published on September 14, 2016 by

The declining value of CD4 counts for antiretroviral therapy eligibility

The World Health Organization’s most recent guideline for the treatment of HIV recommends ART for all individuals living with HIV. Although this new recommendation is gaining traction among wealthier countries, many countries have not yet adopted this guideline. Instead, those countries follow a strategy of providing ART only to people with low CD4+ T-cell counts, which was necessary early in the HIV epidemic, but it is unclear whether the use of CD4 counts was based on sound science and logic.