Published on June 17, 2014 by

The epidemiology of Kaposi sarcoma and Kaposi sarcoma herpesvirus in the setting of the South African HIV epidemic

Kaposi sarcoma (KS) is the most common tumour in HIV-infected individuals in Africa and is preceded by infection with Kaposi sarcoma herpes virus (KSHV). The influence of KS on response to ART is not well defined in resource-limited settings. Additionally, it is unclear if co-infection with oncogenic viruses such as KSHV places untreated HIV-infected patients at increased risk even without clinically apparent illness. The analysis presented here aimed to determine the effect of clinical disease due to KS and also to estimate the impact of co-infection with KSHV among HIV-1 infected adults receiving ART.